2004 OCT 11 - (NewsRx.com & NewsRx.net) -- Anti-idiotypic monoclonal antibodies elicited high molecular weight-melanoma-associated antigen-specific cytotoxic T lymphocytes in patients with melanoma.
"HLA-A2-restricted CTLs, which lysed high molecular weight (HMW)-melanoma-associated antigen (MAA)+ melanoma cells, were induced in patients with melanoma immunized with Melimmune, a combination of the murine anti-idiotypic (anti-id) monoclonal antibodies (mAb) MEL-2 and MF11-30. In the present study we investigated whether CTL epitopes are present in anti-id mAb MF-11-30 and activate T cells to recognize HMW-MAA on melanoma cells," scientists writing in the journal Cancer …
No comments:
Post a Comment